Comorbidity of mental disorders and substance use: a brief guide for the primary care clinician
6.2 Comorbidity with anxiety disorders
- Anxiety frequently occurs in conjunction with other mental disorders, in particularly depression(10, 28, 58, 68, 123, 201, 219-224).
- Anxiety has also been shown to co-occur frequently with suicidality(28, 219) and somatisation disorders(123).
- The presence of anxiety as a comorbidity increases the level of impairment associated with the primary disorder(58, 123).
- Anxiety (particularly PTSD) is commonly seen in association with substance use(10, 11, 23, 28, 29, 68, 121, 196, 221, 224).
- The causal relationship between anxiety disorders and substance use (self-medication theories, substance-induced anxiety) are not clearly established(196).
- Anxiety is also a common feature of substance withdrawal(46, 194, 196).


